Biologic therapy in inflammatory arthritis: BIORES

Status: Ongoing

In this standard of care, umbrella, longitudinal cohort study in rheumatoid arthritis, researchers will take biopsies from patients both before and during treatment during their routine care, to understand why some patients respond better than others, and importantly what goes wrong when a patient doesn’t respond to treatment. This is the first study of its kind systematically analysing tissue samples taken over time.

The findings should help clinical decision making for rheumatoid arthritis patients not responding to first line therapies, so that clinicians can decide whether to change treatment or add an additional drug to help suppress the disease.