Diseases of the immune system which lead to persistent inflammation such as colitis, Crohn’s disease and arthritis, are a group of common and highly disabling conditions which share underlying disease processes. They affect up to 10% of the UK population and this figure is likely to increase with our ageing population. Unfortunately, treatment is expensive, rarely curative and often associated with disabling side-effects such as infection.
The NIHR Birmingham Biomedical Research Centre has exploited the outstanding clinical environment of the University Hospitals Birmingham NHS Foundation Trust and the longstanding research at the University of Birmingham to shed light on the common and distinct mechanisms underpinning these diseases.
Professor David Adams, Director of NIHR Birmingham Biomedical Research Centre, Director of Birmingham Health Partners and Head of the College of Medical and Dental Sciences at the University of Birmingham says: