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Professor Melanie Calvert

Professor Melanie Calvert


Patient-reported Outcomes Theme Lead



Melanie Calvert is Professor of Outcomes Methodology at the University of Birmingham, where she is the Director of the Centre for Patient-Reported Outcomes Research (CPROR). She is also a NIHR Senior Investigator and cross-cutting theme lead for patient-reported outcomes (PROs) research within National Institute for Health and Care Research (NIHR) infrastructure including the BRC, Blood and Transplant Research Unit in Precision and Cellular Therapeutics and Applied Research Collaboration West Midlands.

With international collaborators she led the development of international PRO guidance including the SPIRIT-PRO extension, CONSORT-PRO extension, PRO Ethics Guidelines and is a member of the SISAQOL-IMI initiative. Recent work includes publications on inclusive and equitable PRO data collection, use of PROs in AI studies and real-world evidence generation. Her highly cited work has informed clinical guidelines, NICE and EMA guidance and UK Government policy. Professor Calvert sits on a number of international committees leading national and international strategy for PROs research/implementation, including the PROTEUS Consortium which promotes tools and resources to optimize the use of PROs in clinical trials to ensure that patients, clinicians, and other decision-makers can make the best decisions about treatment options.

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