Women’s metabolic health has long-lasting intergenerational impact, affecting the future health of their children. Birmingham has some of the highest rates of obesity in the UK (59% of women, 26% of children), particularly in women and children of South-Asian and Afro-Caribbean origin. Birmingham also has one of the highest UK birth rates; 45% of mothers were born abroad and 51% live in deprived areas. We propose a woman-centred, integrated life course approach to advance the metabolic health of women and their offspring through early translational and experimental medicine research in areas of greatest need, answering central research questions prioritised through patient and public engagement.
Professor Shakila Thangaratinam