Thrombo-inflammation

Cardiovascular diseases are a major cause of morbidity and mortality and disproportionately affects ethnic minority groups and those socioeconomically deprived. The interplay between inflammation and thrombosis (thrombo-inflammation) plays a critical role in nearly all vascular and heart diseases, and represents a major target for clinical interventions. Moreover, vascular events are a significant driver of prognosis across all chronic inflammatory diseases. Our thrombo-inflammation theme will improve our ability to intercede in clotting whilst avoiding excess bleeding, target underlying inflammatory processes, identify novel biomarkers of thrombo-inflammatory disease, and use artificial intelligence (AI) and innovative trial designs to translate research to better patient care.