Sarcopenia & Multimorbidity

Sarcopenia and multimorbidity are inherent complications of inflammatory diseases, especially in older adults. Over 80% of acute admissions of seniors to University Hospital Birmingham have multimorbidity, with falls a common reason for admission. Additionally, bed rest during a hospital stay results in loss of muscle mass and function, termed acute sarcopenia. Sarcopenia and multimorbidity thus represent significant clinical challenges regionally and nationally. This theme will explore underlying mechanisms and test interventions, cutting across multiple BRC themes, to address our overarching hypotheses.