Newsletter from NIHR BRC: Birmingham: research news, events, and much more

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Research news

clinician using tablet

AI clinical support tool improved clinician decisions in real-world primary care trial

A large real-world clinical trial has found that a generative AI-powered support tool used to support frontline clinicians was safe and improved the quality of clinical decision-making but did not significantly change short-term patient outcomes.

flu virus

Boosting lung defences may protect against respiratory viruses and future pandemics

Researchers from our BRC have been awarded £2.5million of funding from the Advanced Research and Invention Agency (ARIA) to develop a new approach to protecting the lungs against respiratory viral infections.

overweight person pinching stomach

Obesity leaves a lasting memory in immune cells

People who live with obesity are ‘tagging’ a memory of being overweight on a key part of the immune system – leaving people with ongoing risk of obesity-related conditions years after losing weight, according to a 10 year-long study.

dna double helix

Genes link pancreatic cancer with obesity and diabetes

New research shows that the same genes are active in pancreatic cancer, obesity and diabetes, helping to explain why people with metabolic disease often face poorer cancer outcomes and pointing to future ways to predict recurrence and develop more targeted treatments.

elderly man doing hand muscle strength exercises with a ball, assisted by a nurse

Blocking hormone pathway protects against age‑related muscle loss

New research has identified a promising biological pathway that could be targeted to prevent muscle wastage, known clinically as sarcopenia, caused by ageing.

Elderly man being helped by a nurse to walk with a walker in a clinical setting

Muscle loss in liver disease varies by underlying cause

Different types of liver disease are leading to distinct signatures of muscle loss, according to a new study which could help pave the way for more personalised treatments for sarcopenia in people with end‑stage liver disease.


BRC researchers receive funding to improve cancer patients’ lives

Researchers supported by our BRC have secured funding for two new projects to better understand and reduce the side effects of cancer immunotherapy – helping patients to live better during and after treatment.

Dr Claire Palles and Prof Ye Oo standing in a lab

Accolades for our Birmingham experts

Join us in celebrating recent achievements by our researchers, recognising their leadership and impact across clinical practice, research and health policy:

Professor Liz Sapey

Professor Elizabeth Sapey, co-lead of our Infection and Acute Care theme, on being elected as the President of the Association of Physicians of Great Britain & Ireland

Professor Alastair Denniston

Professor Alastair Denniston, co-lead of our Data, Diagnostics and Decision Tools theme, on being recognised as #7 in the Health Service Journal’s “50 most influential people for NHS tech in 2026”, elected as Fellow of the Academy of Medical Sciences, and appointed as lead for the NIHR Health and Social Care Delivery Research programme.

Blogs

A woman wearing a lab coat taking a selfie in a laboratory

PhD Perspectives: Understanding muscle loss in inflammatory disease

In our new PhD Perspectives blog series, we share the research journeys of our BRC-funded PhD students. The first post features Ana Crastin, from our Sarcopenia & Multimorbidity theme, who explores her PhD research on understanding muscle loss in inflammatory disease.

close up of a woman smiling on plain background

Public contributor spotlight: Flic’s take

At the NIHR BRC: Birmingham, we work with patient and public contributors across a range of health conditions. But who are they, and what is it like to get involved in research as a member of the public? To find out, read this piece authored by our public contributor, Flic Gaete.

Events

The thyroid–miscarriage connection: New research and hope for the future 

30 June | 6–7pm | Online

How might thyroid health be linked to miscarriage – even when tests appear normal? Join our next research talk with Dr Rima Dhillon‑Smith from our Women's Metabolic Health theme to explore new research aiming to guide future care for women and families.

In the media

Over the last few months, our research has been making headlines across national and international media:

Genes link pancreatic cancer with obesity and diabetes: Medical Xpress - Metrópoles (Brazil) and many more

Obesity leaves a lasting memory in immune cells: Daily Mail - La Repubblica - Forschung und Wissen and 300+ more

Muscle loss in liver disease varies by underlying cause: Knowridge - Medical Xpress and more


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